Synthesis, Properties and Stereochemistry of 2-Halo-1,2λ⁵-oxaphosphetanes.

Synthesis and Spectral Studies on Thorium (IV) Coordination Compounds of 4-[N-(2-Hydroxybenzalidene)amino] AntipyrineSmeicarbazone and 4-[N-Cinnamalidene) amino] ANtipyrine Semicarbazone

The stereochemistry of the actinide elements has recently undergone considerable development and a wide variety of coordination numbers and geometries have been observed. This structural versatility arises from the lack of strong crystal field effects for the 5f-electronic configurations as well as from the large ionic radii of these metal ions, which change markedly with oxidation number, ...

Synthesis of 4-(2-Methylthiazol-4-yl)-Hexahydroquinoline and 1,4-Dihydropyrimidin Derivatives

A series of new hexahydroquinoline and 1,4-dihydropyrimidine derivatives were synthesized. Condensation of 2-methyl- thiazole-4-carboxaldehyde (1) with 1,3-cyclohexanedione and alkyl 3- aminocrotonate afforded 4-(2-methyl-thiazol-4-yl)-hexahydroquinoline while condensation of aldehyde (1) with benzoyl acetone and thiourea gave 1,4-dihydropyrimidine derivatives. The stereochemistry of 1,4-dihydr...

Synthesis, Stereochemistry and Properties of Some New Spirane-type Compounds Containing 1,3-dioxane Units, and of Some New Macrocycles with Phenothiazine Units

One pot three-component synthesis of imidazole derivatives using NH3/NH4Cl

Imidazole is a planar, five membered heteroaromatic molecule with pyrrole type and pyridine type annular nitrogens. Several approaches are available of imidazoles from alpha halo ketones, aminonitrile, aldehyde ect. Reactivity of imidazole and benzimidazole is referred from sets of  resonance structure in which the dipolar contributors have finite importance. Imidazoles among the principal grou...

Total Synthesis and Stereochemistry of ( + ) - Phyllanthocindiol 843 Paul

The crude ethanol extract obtained from the root of Phyllanthus acuminatus Vahl was found to inhibit growth in the P388 leukemia system in mice. Kupchan and coworkers traced the significant pharmacological properties to a bisabolane sesquiterpene glycoside, (+)-phyllanthoside (0' Although the structure of the corresponding aglycon (+)-phyllanthocin (2) was elucidated by single-crystal X-ray dif...